Lab Members Fred Ausubel

Frederick M. Ausubel

Frederick M. Ausubel

Professor of Genetics
Department of Genetics, Harvard Medical School and
Molecular Biologist
Department of Molecular Biology,Massachusetts General Hospital
50 Blossom Street, Wellman 10
Boston, Massachusetts 02114
Phone:   (617)726-5969
FAX:     (617)726-5949

My Current Curriculum Vitae, updated 2/2000.

Current Research Interests:

We have developed a novel multi-host pathogenesis system that involves the human bacterial pathogens Pseudomonas aeruginosa, Salmonella typhimurium and Enterococcus faecalis to identify virulence-related genes in bacterial pathogens and defense-related genes in four model genetic hosts: the plant Arabidopsis thaliana, the insect Drosophila melanogaster, the nematode Caenorhabditis elegans, and the mammal, Mus musculus. We have identified a set of novel P. aeruginosa genes required for pathogenesis in all of the model hosts and we have isolated Arabidopsis and C. elegans mutants that exhibit aberrant defense responses when challenged with P. aeruginosa.

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Selected Publications List:

See Publications or PubMed