Publications
Breger, J., G. Aperis, B.B. Fuchs, T.I. Moy, F.M. Ausubel and E. Mylonakis (2007) Antifungal chemical compounds identified using a C. elegans pathogenicity assay. PLoS Pathog. 3:e18. doi:10.1371/journal.ppat.0030018 [PubMed] [PLoS] [PDF]
Lee, D.G., N.T. Liberati, J.M. Urbach, G. Wu, and F.M. Ausubel (2007) Modeling microbial virulence in a genomic era: The impact of shared genomic tools and datasets. In: Bacterial Pathogenomics, ASM Press, Washington, DC, pp. 213-231.
Lee, D.G., J.M. Urbach, G. Wu, N.T. Liberati, R.L. Feinbaum and F.M. Ausubel (2007) Combining genomic tools to dissect multifactorial virulence in Pseudomonas aeruginosa. Stadler Symposium Volume, in press.
Begun, J., J.M. Gaiani, H. Rohde, D. Mack, S.B. Calderwood, F.M. Ausubel and C.D. Sifri (2007) Staphylococcal biofilm exopolysaccharide protects against Caenorhabditis elegans immune defenses. PLoS Pathog. 3(4): e57 doi: 10.1371/journal.ppat.0030057 [PubMed] [PLoS] [PDF].
Ferrari, S., R. Galletti, C. Denoux, G. De Lorenzo, F.M. Ausubel and J. Dewdney (2007) Resistance to Botrytis cinerea induced in Arabidopsis thaliana by elicitors is independent of salicylic acid, ethylene or jasmonate signaling but requires PAD3. Plant Physiol. 144: 367-379. [PubMed] [Plant Phys.] [PDF]
Liberati, N.T., J.M. Urbach, T.K. Holmes, G. Wu and F.M. Ausubel (2007) Comparing insertion libraries in two Pseudomonas aeruginosa strains to assess gene essentiality. In: Methods in Molecular Biology, Humana Press, in press.
Powell, J.R. and F.M. Ausubel (2007) Models of Caenorhabditis elegans infection by bacterial and fungal pathogens. In: Methods in Molecular Biology, Humana Press, in press.
Mooij, M.J., E. Drenkard, M.A. Llamas, C.M.J.E. Vandenbroucke-Grauls, P.H.M. Savelkoul, F.M. Ausubel and W. Bitter (2007) Characterization of the integrated filamentous phage PF5 of P. aeruginosa PA14. Microbiology 153: 1790-1798. [PubMed] [Microbiol.]
Bush, J., G. Jander and F.M. Ausubel (2006) Prevention and control of pests and diseases. In: Methods in Molecular Biology, vol. 323: Arabidopsis Protocols, 2nd Edition (J. Salinas and J.J. Sanchez-Serrano, editors) Humana Press, Totowa, NJ, pp. 13-25.
Liberati, N.T., J.M. Urbach, S. Miyata, D.G. Lee, E. Drenkard, G. Wu, J. Villanueva, T. Wei, and F.M. Ausubel (2006) An ordered non-redundant library of Pseudomonas aeruginosa strain PA14 transposon insertion mutants. Proc. Natl. Acad. Sci. USA 103:2833-2838. [PubMed] [PNAS] [PDF]
Kulasakara, H., V. Lee, A. Brencic, N.T. Liberati, J.M. Urbach, S. Miyata, D.G. Lee, A.N. Neely, M. Hyodo, Y. Hayakawa, F.M. Ausubel and S. Lory (2006) Analysis of Pseudomonas aeruginosa diguanylate cyclases and phosphodiesterases reveals a role for bis-(3'-5')-cyclic-GMP in virulence. Proc. Natl. Acad. Sci. USA 103:2839-2844. [PubMed] [PNAS] [PDF]
Mylonakis, E., S.B. Calderwood and F.M. Ausubel (2006) Heterologous hosts and the evolution and study of fungal pathogenesis. In: Molecular Principles of Fungal Pathogenesis (J. Heitman, et al., editors). ASM Press, Washington DC, pp. 215-225.
Moy, T.I., A.R. Ball, Z. Anklesaria, G. Casadei, K. Lewis and F.M. Ausubel (2006). Identification of novel antimicrobials using a live-animal infection model. Proc. Natl. Acad. Sci. USA 103:10414-10419. [PubMed] [PNAS] [PDF]
Bindschedler, L.V., J. Dewdney, K.A. Blee, J.M. Stone, T. Asai, J. Plotnikova, C. Denoux, T. Hayes, C. Gerrish, D.R. Davies, F.M. Ausubel and G.P. Bolwell (2006) Peroxidase-dependent apoplastic oxidative burst in Arabidopsis required for pathogen resistance. Plant J. 47:851-863. [PubMed] [Plant J.] [PDF]
Troemel, E.R., S.W. Chu, V. Reinke, S.S. Lee, F.M. Ausubel and D.H. Kim (2006) p38 MAPK regulates expression of immune response genes and contributes to longevity in C. elegans. PLoS Genet. 2:e183. [PubMed] [PLoS] [PDF]
Ball, A.R., G. Casadei, S. Samosorn, J.B. Bremner, F.M. Ausubel, T.I. Moy, K. Lewis (2006) Conjugating berberine to an MDR pump inhibitor creates an effective antimicrobial. ACS Chem. Biol. 1:594-600. [PubMed] [ACS Chem. Biol.] [PDF]
Lee, D.G., J.M. Urbach, G. Wu, N.T. Liberati, R. Feinbaum, S. Miyata, L.T. Diggins, J. He, M. Saucier, E. Deziel, L. Friedman, L. Li, G. Grills, K. Montgomery, R. Kucherlapati, L.G. Rahme and F.M. Ausubel. (2006) Genomic analysis reveals that Pseudomonas aeruginosa virulence is combinatorial. Genome Biol. 7:R90. [PubMed] [Genome Biol.] [PDF]
Lewis, K. and F.M. Ausubel (2006) Prospects for plant-derived antibacterials. Nature Biotechnology 24:1504-1507. [PubMed] [Nature Biotech.] [PDF]
Kim, D.H. and F.M. Ausubel (2005) Evolutionary perspectives on innate immunity from the study of Caenorhabditis elegans. Curr. Opin. Immunol. 17:4-10. [PubMed] [Curr. Opin. Immunol.] [PDF]
Begun, J., C.D. Sifri, S. Goldman, S.B. Calderwood and F.M. Ausubel (2005) Staphylococcus aureus virulence factors identified using a high throughput Caenorhabditis elegans killing model. Infection and Immunity 73:872-877. [PubMed] [Infect. and Immun.] [PDF]
Cui, J., A.K. Bahrami, E.G. Pringle, G. Hernandez-Guzman, C.L. Bender, N.E. Pierce and F.M. Ausubel (2005) Pseudomonas syringae manipulates systemic plant defenses against pathogens and herbivores. Proc. Natl. Acad. Sci. USA 102:1791-1796. [PubMed] [PNAS] [PDF]
Chang, J.H., J.M. Urbach, T.F. Law, L.W. Arnold, A. Hu, S. Gombar, S.R. Grant, F.M. Ausubel and J.L. Dangl (2005) A high-throughput, near-saturating screen for type III effector genes from Pseudomonas syringae. Proc. Natl. Acad. Sci. USA 102:2549-2554. [PubMed] [PNAS] [PDF]
Sifri, C.D., J. Begun and F.M. Ausubel (2005) The worm has turned – Microbial virulence modeled in Caenorhabditis elegans. Trends in Microbiology, 13:119-127.[PubMed] [Trends in Microbiol.] [PDF]
Bais, H.P., B. Prithiviraj, A.K. Jha, F.M. Ausubel and J.M. Vivanco (2005) Mediation of pathogen resistance by exudation of antimicrobials from roots. Nature 434:217-221. [PubMed] [Nature] [PDF]
Mylonakis, E., R. Moreno, J.B. El Khoury, A. Idnurm, J. Heitman, S.B. Calderwood, F.M. Ausubel and A. Diener (2005). Galleria mellonella as a model system to study Cryptococcus neoformans pathogenesis. Infection and Immunity 73:3842-3850. [PubMed] [Infect. and Immun.] [PDF]
Diener, A. C. and F.M. Ausubel (2005) RESISTANCE TO FUSARIUM OXYSPORUM 1, a dominant Arabidopsis disease-resistance gene, is not race specific. Genetics 171:305-321. [PubMed] [PNAS] [PDF]
Ausubel, F.M. (2005) Are innate immune signaling pathways in plants and animals conserved? Nat. Immunol. 6:973-979. [PubMed] [Nature] [PDF]
Engelbert, M., E. Mylonakis, F.M. Ausubel, S.B. Calderwood, M.S. Gilmore (2004) Contribution of gelatinase, serine protease and fsr to the pathogenesis of Enterococcus faecalis endophthalmitis. Infection and Immunity 72: 3628-3633. [PubMed] [Infect. and Immun.] [PDF]
Tenor, J., B.A. McCormick, F.M. Ausubel, and A. Aballay (2004) Caenorhabditis elegans-based screen identified Salmonella virulence factors required for conserved host-pathogen interactions. Current Biology 14:1018-1024. [PubMed] [Curr. Biol.] [PDF]
Kim, D.H., N.T. Liberati, T. Mizuno, H. Inoue, N. Hisamoto, K. Matsumoto and F.M. Ausubel (2004) Integration of Caenorhabditis elegans MAPK pathways mediating immunity and stress resistance by MEK-1 MAPK kinase and VHP-1 MAPK phosphatase. Proc. Natl. Acad. Sci. USA. 101:10990-10994. [PubMed] [PNAS] [PDF]
Moy, T.I., E. Mylonakis, S.B. Calderwood and F.M. Ausubel (2004) Cytotoxicity from hydrogen peroxide produced by Enterococcus faecium. Infection and Immunity 72:4512-4520. [PubMed] [Infect. and Immun.] [PDF]
Mylonakis, E., A. Idnurm, R. Moreno, J. El Khoury, J.B. Rottman, F.M. Ausubel, J. Heitman and S.B. Calderwood (2004) Cryptococcus neoformans Kin1 protein kinase homologue, identified through a Caenorhabditis elegans screen, promotes virulence in mammals. Molecular Microbiology 54:407-419. [PubMed] [Mol. Microbiol.] [PDF]
Garsin, D.A., J. Urbach, J.C. Huguet-Tapia, J.E. Peters and F.M. Ausubel (2004) Construction of an Enterococcus faecalis Tn917-mediated gene disruption library offers insight into Tn917 insertion patterns. J. Bacteriol. 186:7280-7289. [PubMed] [J. Bacteriol.] [PDF]
Rojo, E., R. Martin, C. Carter, J. Zouhar, S. Pan, J. Plotnikova, H. Jin, M. Paneque, J.J. Sanchez-Serrano, B. Baker, F.M. Ausubel and N. Raikhel (2004) VPEg exhibits a caspase-like activity and triggers defense against pathogens. Current Biology 14:1897-1906. [PubMed] [Current Biol.] [PDF]
Sifri, C.D. and F.M. Ausubel (2004) Use of simple non-vertebrate hosts to model mammalian pathogenesis. In: Cellular Microbiology - Second Edition. (P. Cossart, P. Boquet, S. Normark, and R. Rappuoli, eds.) ASM Press, Washington, D.C., pp 543-563.
Liberati, N.T., K.A. Fitzgerald, D.H. Kim, R. Feinbaum, D.T. Golenbock and F.M. Ausubel (2004) Requirement for a conserved Toll/interleukin-1 resistance domain protein in the Caenorhabditis elegans immune response. Proc. Natl. Acad. Sci. USA. 101(17):6593-8. [PubMed]
[PNAS]
[PDF]
Mizuno,T., N. Hisamoto, T. Terada, T. Kondo, M. Adachi, E. Nishida, D. H. Kim, F.M. Ausubel, and K. Matsumoto (2004) The Caenorhabditis elegans MAPK phosphatase VHP-1 mediates a novel JNK-like signaling pathway in stress response. EMBO J. 23:2226-2234. [PubMed] [EMBO J.] [PDF]
Apidianakis, Y., L.G. Rahme, J. Heitman, F.M. Ausubel, S.B. Calderwood, and E. Mylonakis (2004)
Challenge of Drosophila melanogaster with Cryptococcus neoformans and Role of the Innate Immune Response. Eukaryot. Cell 3(2):413-419. [PubMed] [Eukaryot. Cell] [PDF]
Ferrari, S., J. Plotnikova, G. DeLorenzo and F.M. Ausubel (2003) Arabidopsis local resistance to Botrytis cinerea involves salicylic acid and camalexin and requires EDS4 and PAD2, but not SID2, EDS5 or PAD4. The Plant Journal 35:193-205. [PubMed]
[Plant J.] [PDF]
Garsin, D.A., J. Villanueva, J. Begun, C.D. Sifri, D.H. Kim, S.B. Calderwood, G.B. Ruvkun and F.M. Ausubel (2003) Long-lived C. elegans daf-2 mutants are resistant to bacterial pathogens. Science 300:1921. [PubMed]
[Science]
[PDF]
Miyata, S., M. Casey, D.W. Frank, F.M. Ausubel and E. Drenkard (2003) Use of the Galleria mellonella caterpillar as a model host to study the role of the type III secretion system in Pseudomonas aeruginosa pathogenesis. Infection and Immunity 71:2404-13.
[PubMed]
[Infect. and Immun.] [PDF]
Sifri, C.D., J. Begun, F.M. Ausubel and S.B. Calderwood (2003) Caenorhabditis elegans as a model host for Staphylococcus aureus pathogenesis. Infection and Immunity 71:2208-2217. [PubMed]
[Infect. and Immun.] [PDF]
Alonso, J.M., A. N. Stepanova, R. Solano, E. Wisman, S. Ferrari, F. M. Ausubel and J.R. Ecker (2003) New components of the ethylene signaling pathway uncovered by a novel mutant screen. Proc. Natl. Acad. Sci. USA 100:2992-2997. [PubMed]
[PNAS]
[PDF]
Coleman, F.T., S. Mueschenborn, G. Meluleni, C. Ray, V. Carey, S.O. Vargas, C.L. Cannon, F.M. Ausubel, G.B. Pier (2003) Hypersusceptibility of cystic fibrosis mice to chronic Pseudomonas aeruginosa oropharyngeal colonization and lung infection. Proc. Natl. Acad. Sci. USA 100:1949-1954. [PubMed]
[PNAS]
[PDF]
Ferrari, S., D. Vairo, F.M. Ausubel, F. Cervone and G. De Lorenzo (2003) Differentially regulated Arabidopsis polygalacturonase-inhibiting protein (PGIP) genes encode functional inhibitors capable of limiting fungal infection. Plant Cell 15:93-106. [PubMed]
[Plant
Cell] [PDF]
Aballay, A., E. Drenkard, L.R. Hilbun and F.M. Ausubel (2003) Caenorhabditis elegans innate immune response triggered by Salmonella requires intact LPS and is mediated by a MAPK signaling pathway. Current Biology 13:47-52. [PubMed]
[Current Biol.] [PDF]
Mylonakis, E., F.M. Ausubel, R.J. Tang and S.B. Calderwood (2003) The art of serendipity: killing of Caenorhabditis elegans by human pathogens as a model of bacterial and fungal pathogenesis. Expert Rev Anti Infect. Ther. 1:167-173. [PubMed] [Expert Rev. Anti. Infect. Ther.] [PDF]
Mylonakis, E., F.M. Ausubel, J.R. Perfect, J. Heitman and S.B. Calderwood (2002) Killing of Caenorhabditis elegans by Cryptococcus neoformans as a model of yeast pathogenesis. Proc. Natl. Acad. Sci. USA 99:15675-15680. [PubMed]
[PNAS]
[PDF]
Sifri, C.D., E. Mylonakis, K.V. Singh, X. Qin, D.A. Garsin, B.E. Murray, F.M. Ausubel and S.B. Calderwood (2002). Virulence effect of Enterococcus faecalis protease genes and the quorum-sensing fsr locus in Caenorhabditis elegans and mice. Infection and Immunity 70:5647-5650. [PubMed]
[Infect. and Immun.] [PDF]
Mylonakis, E., M. Engelbert, X. Qin, C.D. Sifri, B.E. Murray, F.M. Ausubel, M.S. Gilmore and S.B. Calderwood. (2002) The Enterococcus faecalis fsrB gene, a key component of the fsr quorum sensing system, is associated with virulence in the rabbit endophthalmitis model. Infection and Immunity 70:4678-4681. [PubMed]
[Infect. and Immun.] [PDF].
Kim, D.H., R. Feinbaum, G. Alloing, F.E. Emerson, D.A. Garsin, H. Inoue, M. Tanaka-Hino, N. Hisamoto, K. Matsumoto, M.-W. Tan and F.M. Ausubel (2002) A conserved p38 MAP kinase pathway in Caenorhabditis elegans innate immunity. Science 297:623-626. [PubMed]
[Science] [PDF]
Cui, J., G. Jander, L. Racki, P.D. Kim, N.E. Pierce and F.M. Ausubel (2002) Signals involved in Arabidopsis resistance to Trichoplusia ni caterpillars induced by virulent and avirulent strains of the phytopathogen Pseudomonas syringae. Plant Physiol. 129:551-564. [PubMed]
[Plant Phys.] [PDF]
Drenkard, E. and F.M. Ausubel (2002) Pseudomonas biofilm formation and antibiotic resistance are linked to phenotypic variation. Nature 416:740-743. [PubMed]
[Nature]
[PDF]
Kudva, I.T., P.S. Evans, N.T. Perna, T.J. Barrett, G.J. DeCastro, F.M. Ausubel, F.R. Blattner and S.B. Calderwood (2002) Polymorphic amplified typing sequences provide a novel approach to Escherichia coli O157:H7 strain typing. J. Clin. Microbiol. 40:1152-1159. [PubMed]
[J. Clin. Microbiol.] [PDF]
Kudva, I.T., P.S. Evans, N.T. Perna, T.J. Barrett, F.M. Ausubel, F.R. Blattner and S.B. Calderwood (2002) Strains of Escherichia coli O157:H7 differ primarily by insertions or deletions, not by single nucleotide polymorphisms. J. Bacteriol. 184:1873-1879. [PubMed]
[J. Bacteriol.] [PDF]
Aballay, A and F.M. Ausubel (2002) Caenorhabditis elegans as a host for the study of host-pathogen interactions. Current Opinion in Microbiology 5:97-101. [PubMed]
[Curr. Opin.] [PDF]
Choi, J.Y., C.D. Sifri, B.C. Goumnerov, L.G. Rahme, F.M. Ausubel and S.B. Calderwood (2002) Identification of virulence genes in a pathogenic strain of Pseudomonas aeruginosa by representational difference analysis. J. Bacteriol. 184:952-961. [PubMed]
[J. Bacteriol.] [PDF]
Asai, T., G. Tena, J. Plotnikova, M.R. Willmann, W.-L. Chiu, L. Gomez-Gomez, T. Boller, F.M. Ausubel and J. Sheen (2002) MAP kinase signaling cascade in Arabidopsis innate immunity. Nature 415:977-983. [PubMed]
[Nature]
[PDF]
Tan, M.-W. and F.M. Ausubel (2002) Alternative models in microbial pathogenesis. In: Methods in Microbiology, Vol. 31, Molecular Cellular Microbiology. (P. Sansonetti and A. Zychlinsky, eds.) Academic Press, San Diego, pp. 461-475.
Hendrickson, E.L., J. Plotnikova, S. Mahajan-Miklos, L.G. Rahme and F.M. Ausubel (2001) Differential roles of the Pseudomonas aeruginosa PA14 rpoN gene in pathogenicity in plants, nematodes, insects and mice. J. Bacteriol. 183:7126-7134. [PubMed]
[J. Bacteriol.] [PDF]
Wildermuth, M.C., J. Dewdney, G. Wu, and F.M. Ausubel (2001) Isochorismate synthase is required to synthesize salicylic acid for plant defense. Nature 414:562-565. [PubMed]
[Nature] [PDF]
Yorgey, P., L.G. Rahme, M.-W. Tan and F.M. Ausubel (2001) The roles of mucD and alginate in the virulence of Pseudomonas aeruginosa in plants, nematodes, and mice. Mol. Microbiol. 41:1063-1076. [PubMed]
[Mol. Microbiol.]
Garsin, D.A., C.D. Sifri, E. Mylonakis, X. Qin, K.V. Singh, B.E. Murray, S.B. Calderwood and F.M. Ausubel (2001) A simple model host for identifying gram-positive virulence factors. Proc. Natl. Acad. Sci. USA 98:10892-10897. [PubMed]
[PNAS]
[PDF]
Jander, G., J. Cui, B. Nhan, N. Pierce and F.M. Ausubel (2001) The TASTY locus on chromosome 1 of Arabidopsis thaliana affects feeding behavior of the insect herbivore Trichoplusia ni. Plant Physiol. 126:890-898. [PubMed]
[Plant
Physiology] [PDF]
Aballay, A. and F.M. Ausubel (2001) Programmed cell death mediated by ced-3 and ced-4 protects Caenorhabditis elegans from Salmonella typhimurium-mediated killing. Proc. Natl. Acad. Sci. USA 98:2735-2739. [PubMed]
[PNAS]
[PDF]
Tao, Y., F. Yuan, R.T. Leister, F.M. Ausubel and F. Katagiri (2000) Mutational analysis of the Arabidopsis nucleotide binding site-leucine-rich repeat resistance gene RPS2. Plant Cell 12:2541-2554. [PubMed]
[The
Plant Cell] [PDF]
Plotnikova, J.M., L.G. Rahme and F.M. Ausubel (2000) Pathogenesis of the human opportunistic pathogen Pseudomonas aeruginosa PA14 in Arabidopsis. Plant Physiol. 124:1766-1774. [PubMed]
[Plant
Physiology] [PDF]
Drenkard, E., B.G. Richter, S. Rozen, L.M. Stutius, N.A. Angell, M. Mindrinos, R.J. Cho, P.J. Oefner, R.W. Davis and F.M. Ausubel (2000) A simple procedure for the analysis of single nucleotide polymorphisms facilitates map-based cloning in Arabidopsis. Plant Physiol. 124:1483-1492. [PubMed]
[Plant
Physiology] [PDF]
Ausubel, F.M. (2000) Arabidopsis Genome: A Milestone in Plant Biology. Plant Physiol. 124:1451-1454. [PubMed]
[Plant
Physiology] [PDF]
Aballay, A., P. Yorgey and F.M. Ausubel (2000) Salmonella typhimurium proliferates and establishes a persistent infection in the intestine of Caenorhabditis elegans. Current Biology 10:1539-1542. [PubMed]
[Science
Direct] [PDF]
Clarke, J.D., S.M. Volko, H. Ledford, F.M. Ausubel and X. Dong (2000) Roles of salicylic acid, jasmonic acid and ethylene in cpr-induced resistance in Arabidopsis. Plant Cell 12:2175-2190. [PubMed]
[Plant
Cell] [PDF]
Dewdney, J., T.L. Reuber, M.C. Wildermuth, A. Devoto, J. Cui, L.M. Stutius, E.P. Drummond, and F.M. Ausubel (2000) Three unique mutants of Arabidopsis identify eds loci required for limiting growth of a biotrophic fungal pathogen. Plant Journal 24:205-218. [PubMed]
[Blackwell
Synergy] [PDF]
Asai, T., J.M. Stone, J.E. Heard, Y Kovtum, P. Yorgey, J. Sheen and F.M. Ausubel (2000) Fumonisin B1-induced cell death in Arabidopsis protoplasts requires jasmonate-, ethylene-, and salicylate-dependent signaling pathways. Plant Cell 12:1823-1836. [PubMed]
[Plant
Cell] [PDF]
Stone, J., J.E. Heard, T. Asai and F.M. Ausubel (2000) Simulation of fungal-mediated host cell death by fumonisin B1 toxin and selection of fumonisin B1-resistant (fbr) Arabidopsis mutants. Plant Cell 12:1811-1822. [PubMed]
[Plant
Cell] [PDF]
Ilag, L.L., R.C. Yadav, N. Huang, P.C. Ronald and F.M. Ausubel (2000) Isolation and characterization of disease resistance gene homologues from rice cultivar IR64. Gene 255:245-255. [PubMed]
[Science
Direct ] [PDF]
Mahajan-Miklos, S., L.G. Rahme and F.M. Ausubel (2000) Elucidating the molecular mechanisms of bacterial virulence using non-mammalian hosts. Molecular Microbiology 37:981-988. [PubMed]
[Blackwell
Synergy ] [PDF]
Keen, N., B. Staskawicz, J. Mekalanos, F. Ausubel, R.J. Cook (2000). Pathogens and hosts: the dance is the same, the couples are different. Proc. Natl. Acad. Sci. USA 97:8752-8753. [PubMed]
[PNAS]
[PDF]
Rahme, L.G., F.M. Ausubel, H. Cao, E. Drenkard, B.C. Goumnerov, G.W. Lau, S. Mahajan-Miklos, J. Plotnikova, M.-W. Tan, M. Tsongalis, C.L. Walendziewicz and R.G. Tompkins (2000) Plants and animals share functionally common bacterial virulence factors. Proc. Natl. Acad. Sci. USA 97:8815-8821. [PubMed]
[PNAS]
[PDF]
Jander, G., L.G. Rahme and F.M. Ausubel (2000) Positive correlation between virulence of Pseudomonas aeruginosa mutants in mice and insects. J. Bacteriol.182:3843-3845. [PubMed]
[Journal
of Bacteriology] [PDF]
Hendrickson, E.L., P. Guevara and F.M. Ausubel (2000) The alternative sigma factor RpoN is required for hrp activity in Pseudomonas syringae pathovar maculicola and acts at the level of hrpL transcription. J. Bacteriol.182:3508-3516. [PubMed]
[Journal
of Bacteriology] [PDF]
Hendrickson, E.L., P. Guevara, A. Peñaloza-Vàzquez, J. Shao, C. Bender and F.M. Ausubel (2000) Virulence of the phytopathogen Pseudomonas syringae pathovar maculicola is rpoN dependent. J. Bacteriol.182:3498-3507. [PubMed]
[Journal
of Bacteriology] [PDF]
Tan, M.-W. and F.M. Ausubel (2000) Caenorhabditis elegans: A model genetic host to study Pseudomonas aeruginosa pathogenesis. Current Opinion in Microbiology 3:29-34. [PubMed] [BioMedNet] [PDF]
Stone, J.M., T. Asai, J.E. Heard and F.M. Ausubel (2000) Investigating the mechanisms of programmed cell death in plants with a toxin from a necrotrophic fungus. In Biology of Plant-Microbe Interactions, volume 2, P.J.G.M. de Wit, T. Bisseling and W.J. Stiekema, eds., APS Press, St. Paul, MN, pp. 411-415.
Jirage, D., T.L. Tootle, T.L. Reuber, L.N. Frost, B.J. Feys, J.E. Parker, F.M. Ausubel and J. Glazebrook (1999) Arabidopsis thaliana PAD4 encodes a lipase-like gene that is important for salicylic acid signaling. Proc. Natl. Acad. Sci. USA 96:13583-8. [PubMed]
[PNAS]
[PDF]
Cho R.J., M. Mindrinos, D.R. Richards, R.J. Sapolsky, M. Anderson, E. Drenkard, J. Dewdney, T.L. Reuber, M. Stammers, N. Federspiel, A. Theologis, W.-H. Yang, E. Hubbell, M. Au, E.Y. Chung, D. Lashkari, B. Lemieux, C. Dean, R.J. Lipshutz, F.M. Ausubel, R.W. Davis, and P.J. Oefner (1999) Genome-wide mapping with biallelic markers in Arabidopsis thaliana. Nature Genetics 23:203-7. [PubMed]
[Nature
Genetics ] [PDF]
Tan, M.-W., L.G. Rahme, J. Sternberg, R.G. Tompkins and F.M. Ausubel. (1999) Pseudomonas aeruginosa killing of Caenorhabditis elegans used to identify P. aeruginosa virulence factors. Proc. Natl. Acad. Sci. USA 96:2408-13. [PubMed]
[PNAS]
[PDF]
Mahajan-Miklos, S., M.-W. Tan, L.G. Rahme and F.M. Ausubel (1999) Molecular mechanisms of bacterial virulence elucidated using a Pseudomonas aeruginosa-Caenorhabdititis elegans pathogenesis model. Cell 96:47-56. [PubMed]
[Cell]
[PDF]
Tan, M.-W., S. Mahajan-Miklos, and F.M. Ausubel (1999) Killing of C. elegans by P. aeruginosa used to model mammalian bacterial pathogenesis. Proc. Natl. Acad. Sci. USA 96:715-720. [PubMed]
[PNAS]
[PDF]
Sanchez, A.C., L.L. Ilag, D. Yang, D. S. Brar, F. Ausubel, G.S. Khush, M. Yano, T. Sasaki, Z. Li, and N. Huang. (1999) Genetic and physical mapping of xa13, a recessive bacterial blight resistance gene in rice. Theoretical and Applied Genetics 98:1022-1028. [Plant
& Animal VII Conference]
Ausubel, F.M. and T. Bisseling (1999) Pathogenesis and symbiosis: two sides of the same coin that should be united by a common web-accessible database. Current Opinion in Plant Biology 2:265-267.
Wong, S.M., P.A. Carroll, F.M. Ausubel and S.B. Calderwood (1998) Modulation of expression of the ToxR regulon in Vibrio cholerae by a member of the two-component family of response regulators. Infection and Immunity 66:5854-5861. [PubMed]
[Infection
and Immunity] [PDF]
Reuber, T.L., J.M. Plotnikova, J. Dewdney, E.E. Rogers, W. Wood, and F.M. Ausubel (1998) Correlation of defense gene induction defects with powdery mildew susceptibility in Arabidopsis enhanced disease susceptibility mutants. Plant Journal 16:473-485. [PubMed]
[Blackwell
Synergy] [PDF]
Glazebrook, J., E. Drenkard, D. Preuss and F.M. Ausubel (1998) Use of cleaved amplified polymorphic sequences (CAPS) as
genetic markers in Arabidopsis thaliana. In: Arabidopsis Protocols (Volume 82 of Methods in Molecular Biology) (J.M. Martínez-Zapater and J. Salinas, eds.) Humana Press, Totowa, NJ, pp.173-182. [PubMed]
Volko, S.M., T. Boller and F.M. Ausubel (1998) Isolation of new Arabidopsis mutants with enhanced disease susceptibility to Pseudomonas syringae by direct screening. Genetics 149:537-548. [PubMed]
[Genetics]
[PDF]
Kubasek, W.L., F.M. Ausubel and B.W. Shirley (1998) A light-independent developmental mechanism potentiates flavonoid gene expression in Arabidopsis seedlings. Plant Molecular Biology 37:217-223. [PubMed]
Pegues, D.A., C. Colby, P.L. Hibberd, L. Glassner-Cohen, F.M. Ausubel, S.B. Calderwood and D.C. Hooper (1998) The epidemiology of resistance to ofloxacin and oxacillin among clinical coagulase-negative staphylococcal isolates: analysis of risk factors and strain types. Clinical Infectious Diseases 26:72-79. [PubMed]
Plotnikova, J.M., T.L. Reuber, F.M. Ausubel and D.H. Pfister (1998) Powdery mildew pathogenesis of Arabidopsis thaliana. Mycologia 90:1009-1016.
Plotnikova, J.M. and F.M. Ausubel (1998) Powdery Mildew Development in Arabidopsis thaliana ecotypes and mutants (in Russian). Mykologiya i Fitopatologiya, v.35, N4, pp.51-57.
Glazebrook, J., E.E. Rogers and F.M. Ausubel (1997) Use of Arabidopsis for genetic dissection of plant defense responses. Annu. Rev. Genet. 31:547-69. [PubMed]
[Annual
Reviews Genetics] [PDF]
Li, J., D.L. Kasper, F.M. Ausubel, B. Rosner, and J.L. Michel (1997) Inactivation of the alpha C protein antigen gene, bca, by a novel shuttle/suicide vector results in attenuation of virulence and immunity in group B Streptococcus. Proc. Natl. Acad. Sci. USA 94:13251-13256. [PubMed]
[PNAS]
[PDF]
Rahme, L.G., M.-W. Tan, L. Le, S.M. Wong, R.G. Tompkins, S.B. Calderwood and F.M. Ausubel (1997) Use of model plant hosts to identify Pseudomonas aeruginosa virulence factors. Proc. Natl. Acad. Sci. USA 94:13245-13250. [PubMed]
[PNAS]
[PDF]
Glazebrook, J., M. Zook, F. Mert, I. Kagan, E.E. Rogers, I.R. Crute, E.B. Holub, R. Hammerschmidt and F. M. Ausubel (1997) Phytoalexin-deficient mutants of Arabidopsis reveal that PAD4 encodes a regulatory factor and that four PAD genes are required for downy mildew resistance. Genetics 146:381-392. [PubMed] [Genetics] [PDF]
Rogers, E.E. and F. M. Ausubel (1997) Arabidopsis enhanced disease susceptibility mutants exhibit enhanced susceptibility to several bacterial pathogens and alterations in PR-1 gene expression. Plant Cell 9:305-316. [PubMed]
[Plant
Cell] [PDF]
Drenkard, E., J. Glazebrook, D. Preuss and F. M. Ausubel (1997) Use of cleaved amplified polymorphic sequences (CAPS) for genetic mapping and typing. In: DNA markers: Protocols, Applications, and Overviews (eds., G, Caetano-Anollés and P.M. Gresshoff) Wiley-VCH, New York, pages 187-197.
Leister, R.T., F.M. Ausubel and F. Katagiri (1996) Molecular recognition of pathogen attack occurs inside plant cells in plant disease resistance specified by the Arabidopsis genes RPS2 and RPM1. Proc. Natl. Acad. Sci. USA 93:15497-15502. [PubMed]
[PNAS]
[PDF]
Calderwood, S.B., M.A. Baker, P.A. Carroll, J.L. Michel, R.D. Arbeit and F.M. Ausubel (1996) Use of cleaved, amplified, polymorphic sequences (CAPS) to distinguish strains of Staphylococcus epidermidis. J. Clin. Microbiol. 34:2860-2865. [PubMed]
[J. Clin. Microbiol.] [PDF]
Rogers, E.E., J. Glazebrook and F.M. Ausubel (1996) Mode of action of the Arabidopsis thaliana phytoalexin camalexin and its role in Arabidopsis-pathogen interactions. Molecular Plant-Microbe Interactions 9:748-757. [PubMed]
Glazebrook, J., E.E. Rogers and F.M. Ausubel (1996) Isolation of Arabidopsis mutants with enhanced disease susceptibility by direct screening. Genetics 143:973-982. [PubMed]
[Genetics]
[PDF]
Reuber, T.L. and F.M. Ausubel (1996) Isolation of Arabidopsis genes that differentiate between resistance responses mediated by the RPS2 and RPM1 disease resistance genes. Plant Cell 8:241-249. [PubMed]
[Plant
Cell] [PDF]
Rogers, E.E., J. Glazebrook, S. Volko and F.M. Ausubel (1996) Arabidopsis thaliana enhanced disease susceptibility (eds) mutants. In: Biology of Plant-Microbe Interactions (Stacey, G., B. Mullin and P. M. Gresshoff, eds.) International Society for Molecular Plant-Microbe Interactions, St. Paul, MN, USA, pp. 47-56.
Leister, R.T., F.M. Ausubel and F. Katagiri (1996) Molecular recognition of pathogen attack occurs inside plant cells in plant disease resistance specified by the Arabidopsis genes RPS2 and RPM1. Proc. Natl. Acad. Sci. USA 93:15497-15502. [PubMed] [PNAS] [PDF]
Shirley, B.W., W.L. Kubasek, G. Storz, E. Bruggemann, M. Koornneef, F.M. Ausubel and H.M. Goodman (1995) Analysis of Arabidopsis mutant deficient in flavonoid biosynthesis. Plant Journal 8:659-671. [PubMed]
[Blackwell
Synergy] [PDF]
Rahme, L., E. Stevens, S. Wolfort, J. Shao, R. Tompkins, and F. M. Ausubel (1995) Common virulence factors for bacterial pathogenicity in plants and animals. Science 268:1899-1902. [PubMed] [Science] [PDF]
Staskawicz, B.J., F. M. Ausubel, B.J. Baker, J.G. Ellis and J.D.G. Jones (1995) Molecular genetics of plant disease resistance. Science 268:661-667. [PubMed] [Science] [PDF]
Reuber, T.L. and F.M. Ausubel (1995) Differential mRNA display. In: Methods in Cell Biology- Vol. 49 (D.W. Galbraith, H. Bohnert and D.P. Borque, eds.) Academic Press, New York, pages 431-440.
Ausubel, F.M., F. Katagiri, M. Mindrinos and J. Glazebrook (1995) Use of Arabidopsis thaliana defense-related mutants to dissect the plant response to pathogens. Proc. Natl. Acad. Sci. USA 92:4189-4196. [PubMed] [PNAS] [PDF]
Hanfstingl, U., A. Berry, E.A. Kellog, J.T. Costa, W. Rüdiger, and F.M. Ausubel (1994) Haplotype divergence coupled with lack of diversity at the Arabidopsis thaliana alcohol dehydrogenase locus: Roles for both balancing and directional selection? Genetics 138:811-828. [PubMed] [Genetics] [PDF]
Mindrinos, M., F. Katagiri, G.-L. Yu, and F.M. Ausubel. (1994) The A. thaliana disease resistance gene RPS2 encodes a protein containing a nucleotide-binding site and leucine-rich repeats. Cell 78:1089-1099. [PubMed]
[Cell] [PDF]
Glazebrook, J. and F.M. Ausubel (1994) Isolation of phytoalexin-deficient mutants of Arabidopsis thaliana and characterization of their interactions with bacterial pathogens. Proc. Natl. Acad. Sci. USA 91:8955-8959. [PubMed]
[PNAS]
[PDF]
Greenberg, J.T., A. Guo, D.F. Klessig, and F.M. Ausubel (1994) Programmed cell death in plants: A pathogen-triggered response activated coordinately with multiple defense functions. Cell 77:551-563. [PubMed]
[Cell] [PDF]
Crute, I., J. Beynon, J. Dangl, E. Holub, B. Mauch-Mani, A. Slusarenko, B. Staskawicz, and F. Ausubel (1994). Microbial pathogenesis of Arabidopsis. In: Arabidopsis (E. Meyerowitz and C. Somerville, eds.) Cold Spring Harbor Laboratory Press, New York, pp. 705-747.
Mindrinos, M., F. Katagiri, G. Glazebrook, J. and F.M. Ausubel, F (1994). Identification and characterization of an Arabidopsis ecotype which fails to mount a hypersensitive response when infiltrated with Pseudomonas syringae strains carrying avrRpt2. In: Advances in Molecular Genetics of Plant-Microbe Interactions, Vol. 3 (M. Daniels, J. A. Downie, and A.E. Osbourn, eds.) Kluwer Academic Publishers, Dordrecht, pp. 253-260.
Michel, J.L., B.D. Beseth, L.C. Madoff, S.K. Olsen, D.L. Kasper and F.M. Ausubel (1994) Genotypic diversity and evidence for two distinct classes of the C protein alpha antigen of group B Streptococcus. In: Pathogenic Streptococci: Present and Future (A.A. Totolian, ed.) Lancer Publications, St. Petersburg, Russia, pp. 331-332.
Horensky, D.S., J.L. Michel, F.M. Ausubel, D.L. Kasper and L.C. Madoff (1994) Constructs of group B streptococcal alpha C protein containing variable numbers of tandem repeats express immunoreactive protein products. In: Pathogenic Streptococci: Present and Future (A.A. Totolian, ed.) Lancer Publications, St. Petersburg, Russia, pp. 311-313.
Susek, R.E., F.M. Ausubel, and J. Chory (1993) Signal transduction mutants of Arabidopsis uncouple CAB and RBCS gene expression from chloroplast development. Cell 74:787-799. [PubMed]
[Cell] [PDF]
Yu, G.-L., F. Katagiri, and F.M. Ausubel (1993) Arabidopsis mutations at the RPS2 locus result in loss of resistance to Pseudomonas syringae strains expressing the avirulence gene avrRpt2. Molecular Plant-Microbe Interactions 6:434-443. [PubMed] [PDF]
Konieczny, A. and F.M. Ausubel (1993) A procedure for mapping Arabidopsis mutations using co-dominant ecotype-specific PCR-based markers. Plant Journal 4:403-410. [PubMed]
[Blackwell
Synergy] [PDF]
Greenberg, J.T. and F.M. Ausubel (1993) Arabidopsis mutants compromised for the control of cellular damage during pathogenesis and aging. Plant Journal 4:327-341. [PubMed]
[Blackwell
Synergy] [PDF].
Melan, M.A., X. Dong, M.E. Endara, K.R. Davis, F.M. Ausubel, and T.K. Peterman (1993) An Arabidopsis thaliana lipoxygenase gene can be induced by pathogens, abscisic acid and methyl jasmonate. Plant Physiol. 101:441-450. [PubMed]
[Plant
Physiology] [PDF]
Michel, J.L., B.D. Beseth, L.C. Madoff, S.K. Olsen, D.L. Kasper and F.M. Ausubel (1993) Two distinct classes of the C protein alpha antigen of group B Streptococcus display phenotypic and genotypic diversity. Clin. Infect. Dis. 17(3):531.
Mindrinos, M.N., G.-L. Yu and F.M. Ausubel (1993) Arabidopsis thaliana as a model system to study host pathogenic bacterial interaction. In: Arabidopsis thaliana as a Model for Plant-Pathogen Interactions (K.R. Davis and R. Hammerschmidt, eds.) APS Press, St. Paul, Minnesota, pp. 37-48.
Ausubel, F.M., J. Glazebrook, J. Greenberg, M. Mindrinos, and G.-L. Yu (1993) Analysis of the Arabidopsis defense response to Pseudomonas pathogens. In: Advances in Molecular Genetics of Plant-Microbe Interactions, Vol. 2 (E.W. Nester and D.P.S. Verma, eds.) Kluwer Academic Publishers, Dordrecht, pp. 383-404.
Michel, J.L., L.C. Madoff, K.J Olson, D.E. Kling, D.L. Kasper, and F.M. Ausubel (1992) Large identical tandem repeating units in the C protein alpha antigen gene, bca, of Group B Steptococci. Proc. Natl. Acad. Sci. USA 89:10060-10064. [PubMed]
[PNAS]
[PDF].
Voytas, D.F., M.P. Cummings, A. Konieczny, F. M. Ausubel, and S. R. Rodermel (1992) copia-like retrotransposons are ubiquitous among plants. Proc. Natl. Acad. Sci. USA 89:7124-7128. [PubMed]
[PNAS]
[PDF]
Huala, E., J. Stigter, and F.M. Ausubel (1992) The central domain of Rhizobium leguminosarum DctD functions independently to activate transcription. J. Bacteriol. 174:1428-1431. [PubMed] [J. Bacteriol.] [PDF]
Kubasek, W.L., B.W. Shirley, A. Mckillop, H.M. Goodman, W. Briggs, and F.M. Ausubel (1992) Regulation of flavonoid biosynthetic genes in germinating Arabidopsis seedlings. Plant Cell 4:1229-1236. [PubMed] [Plant Cell] [PDF]
Sun, T.-P., H.M. Goodman, and F.M. Ausubel (1992) Cloning the Arabidopsis GA1 locus by genomic subtraction. Plant Cell 4:119-128. [PubMed] [Plant Cell] [PDF]
Sun, T.-P, D. Straus, and F.M. Ausubel (1992) Cloning Arabidopsis genes by genomic subtraction. In: Methods in Arabidopsis Research (C. Koncz, J. Schell and N.-H. Chua, eds.) World Scientific Publishing, Singapore, pp-331-341.
Dickstein, R., D.C. Scheirer, W.H. Fowle, and F.M. Ausubel (1991) Nodules elicited by Rhizobium meliloti heme mutants are arrested at an early stage of development. Molec. Gen. Genet. 230:423-432. [PubMed] [Mol. Gen. Genet.]
Keith, B., X. Dong, F.M. Ausubel, and G.R. Fink (1991) Differential induction of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase genes in Arabidopsis thaliana by wounding and pathogen attack. Proc. Natl. Acad. Sci. USA 88:8821-8825. [PubMed]
[PNAS]
[PDF].
Michel, J.L., L.C. Madoff, D.E. Kling, D.L. Kasper, and F.M. Ausubel (1991) Cloned alpha and beta antigens of a group B streptococci elicit protective immunity. Infect. Immun. 59:2023-2028. [PubMed] [Infect. Immun.] [PDF]
Feinbaum, R.L., G. Storz, and F.M. Ausubel (1991) High intensity and blue light regulated expression of chimeric chalcone synthase genes in transgenic Arabidopsis thaliana plants. Molec. Gen. Genet. 226:449-456. [PubMed]
Konieczny, A., D.F. Voytas, M.P. Cummings, and F.M. Ausubel (1991) A Superfamily of Arabidopsis thaliana retrotransposon. Genetics 127:801-809. [PubMed] [Genetics] [PDF]
Huala, E., A. Moon, and F.M. Ausubel (1991) Aerobic inactivation of Rhizobium meliloti nifA in Escherichia coli is mediated by lon and two newly identified genes, snoB and snoC. J. Bacteriol. 173:382-390. [PubMed] [J. Bacteriol.] [PDF]
Dong, X., M. Mindrinos, K.R. Davis, and F.M. Ausubel (1991) Induction of Arabidopsis thaliana defense genes by virulent and avirulent Pseudomonas syringae strains and by a cloned avirulence gene. Plant Cell 3:61-72. [PubMed]
[Plant
Cell] [PDF]
Davis, K.R., E. Schott, and F.M. Ausubel (1991) Virulence of selected phytopathogenic pseudomonads in Arabidopsis thaliana. Molecular Plant-Microbe Interactions 4:477-488. [MPMI] [PDF]
Richards, E.J., H.M. Goodman, and F.M. Ausubel (1991) The centromere regions of Arabidopsis thaliana chromosome 1 contains telomere-similar sequences. Nucleic Acids Research 19:3351-3357. [PubMed] [Nucl. Acids Res.] [PDF]
Michel, J.L., L.C. Madoff, D.E. Kling, D.L., Kasper, and F.M. Ausubel (1991) Characterization of the native and cloned C protein antigens of group B Streptococcus. In: New Perspectives on Streptococci and Streptococcal Infections (G. Orefici, ed.) Gustav Fisher Verlag, New York, pp. 366-367.
Madoff, L.C., J.L. Michel, S. Hori, F.M. Ausubel, and D.L. Kasper (1991) The cloned and native beta antigens of the group B streptococcal C protein: Role in protective immunity. In: New Perspectives on Streptococci and Streptococcal Infections (G. Orefici, ed.) Gustav Fisher Verlag, New York, pp. 363-365.
Ausubel, F.M., K.R. Davis, E.J. Schott, X. Dong, and M. Mindrinos (1991) Identification of signal transduction pathways leading to the expression of Arabidopsis thaliana defense genes. In: Advances in Molecular Genetics of Plant-Microbe Interactions (H. Hennecke and D.P.S. Verma, eds.) Kluwer Academic Publishers, Dordrecht, pp. 357-364.
Michel, J.L., L.C. Madoff, D.E. Kling, D.L. Kasper, and F.M. Ausubel (1991) C proteins of group B Streptococci. In: Genetics and Molecular Biology of Streptococci, Lactococci, and Enterococci (G.M. Dunny, P.C. Cleary and L.L. McKay, eds.) American Society for Microbiology, Washington DC, pp. 214-218.
Voytas, D.F., A. Konieczny, M.P. Cummings, and F.M. Ausubel (1990) The structure, distribution, and evolution of the Ta1 retrotransposable element family of Arabidopsis thaliana. Genetics 126:713-721. [PubMed] [Genetics] [PDF]
Straus, D., and F.M. Ausubel (1990) Genomic subtraction for cloning DNA corresponding to deletion mutations. Proc. Natl. Acad. Sci. USA 87:1889-1893. [PubMed]
[PNAS]
[PDF].
Honma, M.A., and F.M. Ausubel (1990) Rhizobium meliloti nodD genes mediate host-specific activation of nodABC. J. Bacteriol. 172:901-911. [PubMed] [J. Bacteriol.] [PDF]
Schott, E.J., K.R. Davis, X. Dong, M. Mindrinos, P. Guevara, and F.M. Ausubel (1990) Pseudomonas syringae infection of Arabidopsis thaliana as a model system for studying plant-bacterial interactions. In: Pseudomonas: Biotransformation, Pathogenesis, and Evolving Biotechnology (S. Silver, A.M. Chakrabarty, B. Iglewski, and S. Kaplan, eds.) American Society for Microbiology, Washington, D.C. pp. 82-90.
Konieczny, A., D.V. Voytas, and F.M. Ausubel (1990) Retrotransposable elements in Arabidopsis thaliana. In: Plant Gene Transfer (C.J. Lamb and R.N. Beachy, eds.) Wiley-Liss, New York, pp. 65-70.
Chory, J., C.A. Peto, R. Feinbaum, L. Pratt, and F.M. Ausubel (1989) Arabidopsis thaliana mutant that develops as a light-grown plant in the absence of light. Cell 58:991-999. [PubMed]
[Cell]
Bloch, C.A., G.M. Thorne, and F.M. Ausubel (1989) A general method for site-directed mutagenesis in Escherichia coli O18ac:K1:H7: Deletion of the inducible superoxide dismutase gene, sodA, does not diminish bacteremia in neonatal rats. Infect. Immun. 57:2141-2148. [PubMed] [Infect. Immun.] [PDF]
Huala, E., and F.M. Ausubel (1989) The central domain of Rhizobium meliloti nifA is sufficient to activate transcription from the R. meliloti nifH promoter. J. Bacteriol. 171:3354-3365. [PubMed] [J. Bacteriol.] [PDF]
Olszewski, N.E., R.T. Gast, and F.M. Ausubel (1989) A dual labeling method for identifying differentially-expressed genes: Use in identification of cDNA clones that hybridize to RNAs whose abundance in tomato flowers is potentially regulated by gibberellins. Gene 77:155-162. [PubMed] [Gene] [PDF]
Albright, L.M., C.W. Ronson, B.T. Nixon, and F.M. Ausubel (1989) Identification of a gene linked to Rhizobium meliloti ntrA whose product is homologous to a family of ATP-binding proteins. J. Bacteriol. 171:1932-1941. [PubMed] [J. Bacteriol.] [PDF]
de Bruijn, F.J., S. Rossbach, M. Schneider, P. Ratet, S. Messmer, W.W. Szeto, F.M. Ausubel, and J. Schell (1989) Rhizobium meliloti has three differentially regulated loci involved in glutamine biosynthesis, none of which is essential for symbiotic nitrogen fixation. J. Bacteriol. 171:1673-1682. [PubMed] [J. Bacteriol.] [PDF]
Albright, L.M., E. Huala, and F.M. Ausubel (1989) Prokaryotic signal transduction mediated by sensor and regulator protein pairs. Annu. Rev. Genet. 23:311-336. [PubMed] [Ann. Rev. Genet.]
Davis, K.R., and F.M. Ausubel (1989) Characterization of elicitor-induced defense responses in suspension-cultured cells of Arabidopsis. Molecular Plant-Microbe Interactions 2:363-368. [MPMI] [PDF]
Davis, K.R., E. Schott, X. Dong, and F.M. Ausubel (1989) Arabidopsis thaliana as a model system for studying plant-pathogen interactions. In: Signal Molecules in Plants and Plant-Microbe Interactions (B.J.J. Lugtenberg, ed.) Springer-Verlag, Berlin, pp. 99-106.
Chory, J., C.A. Peto, M. Ashbaugh, R. Saganich, L. Pratt, and F.M. Ausubel (1989) Different roles for phytochrome in etiolated and green plants deduced from characterization of Arabidopsis thaliana mutants. Plant Cell 1:867-880. [PubMed] [Plant Cell] [PDF]
Debelle, F., F. Maillet, J. Vasse, C. Rosenberg, F. De Billy, G. Truchet, J. Denarie, and F.M. Ausubel (1988) Interference between Rhizobium meliloti and R. trifolii nodulation genes: The genetic basis of R. meliloti dominance. J. Bacteriol. 170:5718-5727. [PubMed] [J. Bacteriol.] [PDF]
Olszewski, N.E., F.B. Martin, and F.M. Ausubel (1988) Specialized binary vector for plant transformation: expression of the Arabidopsis thaliana AHAS gene in Nicotiana tabacum. Nucleic Acids Research 16:10765-10781. [PubMed] [Nucl. Acids. Res.] [PDF]
Voytas, D.V., and F.M. Ausubel (1988) A copia-like retrotransposon family in Arabidopsis thaliana. Nature 336:242-244. [PubMed]
Dickstein, R., T. Bisseling, V. Reinhold, and F.M. Ausubel (1988) Expression of nodule-specific genes in alfalfa root nodules blocked at an early stage of development. Genes & Development 2:677-687. [PubMed]
Feinbaum, R., and F.M. Ausubel (1988) Transcriptional regulation of the Arabidopsis thaliana chalcone synthase gene. Molecular and Cellular Biology 8:1985-1992. [PubMed]
Richards, E. J., and F.M. Ausubel (1988) Isolation of a higher eukaryotic telomere from Arabidopsis thaliana. Cell 53:127-136. [PubMed]
[Cell]
Dunn, K., R. Dickstein, R. Feinbaum, B.K. Burnett, T.K. Peterman, G. Thoidis, H.M. Goodman, and F.M. Ausubel (1988) Developmental regulation of nodule-specific genes in alfalfa root nodules. Molecular Plant-Microbe Interactions 1:66-74. [PubMed]
Albright, L.M., E. Huala, Q. Gu, and F.M. Ausubel (1988) Regulation of R. meliloti nifA function, In: Nitrogen Fixation: Hundred Years After, Proceedings of the 7th International Congress on Nitrogen Fixation (H. Bothe, F.J. de Bruijn and W.E. Newton, eds.), Fischer, Stuttgart, pp. 345-349.
Honma, M.A., and F.M. Ausubel (1987) Rhizobium meliloti has three functional copies of the nodD symbiotic gene. Proc. Natl. Acad. Sci. USA 84:8558-8562. [PubMed] [PNAS] [PDF]
Ronson, C.W., P.M. Astwood, B.T. Nixon, and F.M. Ausubel (1987) Deduced products of C4-dicarboxylate transport regulatory genes of Rhizobium leguminosarum are homologous to nitrogen regulatory gene products. Nucleic Acids Research 15:7921-7934. [PubMed] [Nucl. Acids. Res.] [PDF]
Ronson, C.W., B.T. Nixon, and F.M. Ausubel (1987) Conserved domains in bacterial regulatory proteins that respond to environmental stimuli. Cell 49:579-581. [PubMed]
[Cell] [PDF]
Ronson, C.W., B.T. Nixon, L.M. Albright, and F.M. Ausubel (1987) Rhizobium meliloti ntrA (rpoN) gene is required for diverse metabolic functions. J. Bacteriol. 169:2424-2431. [PubMed] [J. Bacteriol.] [PDF]
Wilson, K.J., V. Anjaiah, P.T.C. Nambiar, and F.M. Ausubel (1987) Isolation and characterization of symbiotic mutants of Bradyrhizobium sp. (Arachis) strain NC92: Mutants with host-specific defects in nodulation and in nitrogen fixation. J. Bacteriol. 169:2177-2186. [PubMed] [J. Bacteriol.] [PDF]
Szeto, W.W. B.T. Nixon, C.W. Ronson, and F.M. Ausubel (1987) Identification and characterization of the Rhizobium meliloti ntrC gene: R. meliloti has separate regulatory pathways for activation of nitrogen fixation genes in free-living and symbiotic cells. J. Bacteriol. 169:1423-1432. [PubMed] [J. Bacteriol.] [PDF]
Earl, C.D., C.W. Ronson, and F.M. Ausubel (1987) Genetic and structural analysis of the Rhizobium meliloti fixA, fixB, fixC and fixX genes. J. Bacteriol. 169:1127-1136. [PubMed] [J. Bacteriol.] [PDF]
Buikema, W.J., J.A. Klingensmith, S.L. Gibbons, and F.M. Ausubel (1987) Conservation of structure and location of Rhizobium meliloti and Klebsiella pneumoniae nifB genes. J. Bacteriol. 169:1120-1126. [PubMed] [J. Bacteriol.] [PDF]
Ausubel, F.M., R. Brent, R.E. Kingston, D.D. Moore, J.G. Seidman, J.A. Smith, and K. Struhl (1987) Current Protocols in Molecular Biology, Greene Publishing Associates/Wiley Interscience, New York.
F.M. Ausubel, M.A. Honma, R. Dickstein, W.W. Szeto, B.T. Nixon, and C.W. Ronson (1987) Plant-bacterial signaling in the Rhizobium-legume symbiosis. In: Plant Molecular Biology (D. von Wettstein and N.-H. Chua, eds.), Plenun Press, New York and London, pp. 531-539.
Olszewski, N., D.V. Voytas, J. Hu, J. Chory, and F.M. Ausubel (1987) Construction and testing of vectors for the cloning of plant genes by phenotypic complementation. In: Molecular Biology of Plant Growth Control (J.E. Fox and M. Jacobs, eds.), Alan R. Liss, New York, pp. 145-155.
Marvel, D.J., J.G. Torrey, and F.M. Ausubel (1987) Rhizobium symbiotic genes required for nodulation of legume and nonlegume hosts. Proc. Natl. Acad. Sci. USA 84:1319-1323. [PubMed] [PNAS] [PDF]
Honma, M.A., and F.M. Ausubel (1987) Host specific nodulation: Effects of multiple nodD genes of Rhizobium meliloti. In: Molecular Genetics of Plant-Microbe Interactions (D.P.S. Verma and N. Brisson, eds.) Martinus Nijhoff Publishers, Dordrecht, The Netherlands, pp. 123-124.
Chory, J., D.V. Voytas, N.E. Olszewski, and F.M. Ausubel (1987) Gibberellin-induced changes in the populations of translatable mRNAs and accumulated polypeptides in dwarfs of maize and pea. Plant Physiology 83:15-23. [PubMed] [Plant Phys.] [PDF]
Bloch, C.A., and F.M. Ausubel (1986) Paraquat-mediated selection for mutations in the manganese-superoxide dismutase gene sodA. J. Bacteriol. 168:795-798. [PubMed] [J. Bacteriol.] [PDF]
Nixon, B.T., C.W. Ronson, and F.M. Ausubel (1986) Two-component regulatory systems responsive to environmental stimuli share strongly conserved domains with the nitrogen assimilation regulatory genes ntrB and ntrC. Proc. Natl. Acad. Sci. USA 83:7850-7854. [PubMed] [PNAS] [PDF]
Ausubel, F.M. (1986) Biological nitrogen fixation - Recent advances and future prospects. Regulatory Toxicology and Pharmacology 6:1-10. [PubMed] [Science Direct]
Gussin, G.N., C.W. Ronson, and F.M. Ausubel (1986) Regulation of nitrogen fixation genes. Ann. Rev. Genet. 20:567-591. [PubMed] [Ann. Rev. Genet.]
Bloch, C.A., and F.M. Ausubel (1986) Paraquat-mediated selection for mutations in a cloned manganese-superoxide dismutase gene. In: Superoxide Dismutase in Chemistry, Biology and Medicine (G. Rotilio, ed.) Elsevier Biomedical Press, pp. 293-295.
Buikema, W.J., W.W. Szeto, P.V. Lemley, W.H. Orme-Johnson, and F.M. Ausubel (1985) Nitrogen fixation specific regulatory genes of Klebsiella pneumoniae and Rhizobium meliloti share homology with the general nitrogen regulatory gene ntrC of K. pneumoniae. Nucleic Acids Res. 13:4539-4555. [PubMed] [Nucl. Acids. Res.]
Lang-Unnasch, N., K. Dunn, and F.M. Ausubel (1985) Symbiotic nitrogen fixation: developmental genetics of nodule formation. Cold Spring Harbor Symp. Quant. Biol. 50:555-563. [PubMed]
Ausubel, F.M., W.J. Buikema, C.D. Earl, J.A. Klingensmith, B.T. Nixon, and W.W. Szeto (1985) Organization and regulation of Rhizobium meliloti and Parasponia Bradyrhizobium nitrogen fixation genes. In: Nitrogen Fixation Research Progress (H.J. Evans, P.J. Bottomley and W.E. Newton, eds.) Martinus Nijhoff, Dordrecht, The Netherlands, pp. 165-171.
Wilson, K.J., V. Anjaiah, P.T.C. Nambiar, and F.M. Ausubel (1985) Transposon mutagenesis of slow-growing Rhizobium strain NC92: Isolation and characterization of host specific nodulation (nod) and nitrogen fixation (fix) deficient mutants. In: Nitrogen Fixation Research Progress (H.J. Evans, P.J. Bottomley and W.E. Newton, eds.) Martinus Nijhoff, Dordrecht, The Netherlands, p. 131.
Honma, M.A., C.A. Smith, A.M. Hirsch, N. Lang-Unnasch, and F.M. Ausubel (1985) Identification of Rhizobium meliloti nodulation genes. In: Nitrogen Fixation Research Progress (H.J. Evans, P.J. Bottomley and W.E. Newton, eds.) Martinus Nijhoff, Dordrecht, The Netherlands, p. 120.
Marvel, D.J., G. Kuldau, A.M. Hirsch, E. Richards, J.G. Torrey, and F.M. Ausubel (1985) Conservation of nodulation genes between Rhizobium meliloti and a slow-growing Rhizobium strain that nodulates a non-legume host. Proc. Natl. Acad. Sci. USA 82:5841-5845. [PubMed] [PNAS] [PDF]
Marvel, D.J., F.M. Ausubel, G. Kuldau, and A.M. Hirsch (1985) Evidence for structural and functional conservation between common nodulation genes of fast growing Rhizobia and a nodulation locus from Rhizobium parasponium. In: Advances in the Molecular Genetics of the Bacteria-Plant Interaction (A.A. Szalay and R.P. Legocki, eds.) Cornell University Publishers, Ithaca, pp. 56-57.
Buikema, W.J., W.W. Szeto, and F.M. Ausubel (1985) nif-specific regulatory proteins of Klebsiella pneumoniae and Rhizobium meliloti share homology with the K. pneumoniae ntrC gene. In: Advances in the Molecular Genetics of the Bacteria-Plant Interaction (A.A. Szalay and R.P. Legocki, eds.) Cornell University Publishers, Ithaca, pp. 10-12.
Lang-Unnasch, N., and F.M. Ausubel (1985) Nodule-specific polypeptides from effective alfalfa root nodules and from ineffective nodules lacking nitrogenase. Plant Physiol. 77:833-839. [PubMed] [Plant Phys.] [PDF]
Hirsch, A.M., K. Wilson, J.D.G. Jones, M. Bang, V.V. Walker, and F.M. Ausubel (1984) Rhizobium meliloti nodulation genes allow Agrobacterium tumefaciens and Escherichia coli to form pseudo nodules on alfalfa. J. Bacteriol. 158:1133-1143. [PubMed]
Ausubel, F.M. (1984) Regulation of nitrogen fixation genes. Cell 37:5-6. [PubMed]
[Cell]
Szeto, W.W., J.L. Zimmerman, V. Sundaresan, and F.M. Ausubel (1984) A Rhizobium meliloti symbiotic regulatory gene. Cell 36:1035-1043. [PubMed]
[Cell]
Brown, S.E., and F.M. Ausubel (1984) Mutations affecting regulation of the Klebsiella pneumoniae nifH (nitrogenase reductase) promoter. J. Bacteriol. 157:143-147. [PubMed]
Skvirsky, R.C., M.R. Hanson, and F.M. Ausubel (1984) Intraspecific genetic variation in cytokinin-controlled shoot morphogenesis from tissue explants of Petunia hybrida. Plant Science Lett. 35:237-246.
Szeto, W.W., J.L. Zimmerman, V. Sundaresan, and F.M. Ausubel (1984) A Rhizobium meliloti symbiotic gene that regulates other nitrogen fixing genes. In: Molecular Biology of Development (E.H. Davidson and R.A. Firtel, eds.) Alan R. Liss, New York, pp. 611-617.
Ausubel, F.M. (1984) Developmental genetics of the Rhizobium-legume symbiosis. In: Microbial Development (R. Losick and L. Shapiro, eds.) Cold Spring Harbor Press, Cold Spring Harbor, pp. 275-298.
Lang-Unnasch, N., and F.M. Ausubel (1984) Alfalfa nodulins from effective and ineffective symbioses. In: Advances in Nitrogen Fixation Research (C. Veeger and W.E. Newton, eds.) Nijhoff Junk, The Hague, p. 600.
Marvel, D.J., G. Kuldau, A.M. Hirsch, J. Park, J.G. Torrey, and F.M. Ausubel (1984) Cloning and characterization of a nodulation locus from Rhizobium parasponium. In: Advances in Nitrogen Fixation Research (C. Veeger and W.E. Newton, eds.) Nijhoff Junk, The Hague, p. 691.
de Bruijn, F.J., V. Sundaresan, W.W. Szeto, D.W. Ow, and F.M. Ausubel (1984) Regulation of the nitrogen fixation (nif) genes of Klebsiella pneumoniae and Rhizobium meliloti: Role of nitrogen regulation (ntr) genes. In: Advances in Nitrogen Fixation Research (C. Veeger and W.E. Newton, eds.) Nijhoff Junk, The Hague, pp. 627-633.
Zimmerman, J.L., W.W. Szeto, and F.M. Ausubel (1983) Molecular characterization of Tn5-induced symbiotic (Fix-) mutants of Rhizobium meliloti. J. Bacteriol. 156:1025-1034. [PubMed] [J. Bacteriol.] [PDF]
Ow, D.W., and F.M. Ausubel (1983) Conditionally replicating plasmid vectors that can integrate into the Klebsiella pneumoniae chromosome via bacteriophage P4 site-specific recombination. J. Bacteriol. 155:704-713. [PubMed] [J. Bacteriol.] [PDF]
Hirsch, A.M., M. Bang, and F.M. Ausubel (1983) Ultrastructural analysis of ineffective alfalfa nodules formed by nif::Tn5 mutants of Rhizobium meliloti. J. Bacteriol. 155:367-380. [PubMed] [J. Bacteriol.] [PDF]
Sundaresan, V., D.W. Ow, and F.M. Ausubel (1983) Activation of Klebsiella pneumoniae and Rhizobium meliloti nitrogenase promoters by gln (ntr) regulatory proteins. Proc. Natl. Acad. Sci. USA 80:4030-4034. [PubMed] [PNAS] [PDF]
Ow, D.W., V. Sundaresan, D. Rothstein, S.E. Brown, and F.M. Ausubel (1983) Promoters regulated by the glnG (ntrC) and nifA gene products share a heptameric consensus sequence in the -15 region. Proc. Natl. Acad. Sci. USA 80:2524-2528. [PubMed] [PNAS] [PDF]
Sundaresan, V., J.D.G. Jones, D.W. Ow, and F.M. Ausubel (1983) Klebsiella pneumoniae nifA product activates the Rhizobium meliloti nitrogenase promoter. Nature 301:728-732. [PubMed] [Nature] [PDF]
Ow, D.W., and F.M. Ausubel (1983) Regulation of nitrogen metabolism by nifA gene product in Klebsiella pneumoniae. Nature 301:307-313. [PubMed]
Buikema, W.J., S.R. Long, S.E. Brown, R.C. van den Bos, C.D. Earl, and F.M. Ausubel (1983) Physical and genetic characterization of Rhizobium meliloti sym